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The mechanism of this disease is not entirely clear, at present recognized the pathogenesis of disease include the following four aspects.

1, the Department of hair follicles funnel hyperkeratosis
Under normal circumstances, only the Department of funnel in the hair follicles of non-adhesive cell Diagonalization of single-cell and off into the cavity. In the beginning of the formation of acne, keratosis of the terminal phase of the cell took place obstacles to form a micro acne.

2, the male hormone and sebaceous hyperthyroidism
The sebaceous gland growth and differentiation from the male hormone regulation and control, the complex mechanism, but not yet fully understand.

3, sebaceous hair follicle unit in the role of micro-organisms
Sebum in the hair follicle unit at least three types of parasitic micro-organisms, and that is: staphylococcus, yeast and acid bacteria. And the incidence of acne is a relatively close relationship spp acid.

4, inflammation and host immune response.

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