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Quite a number of diseases can change the normal color to black, and even grow speckle. One of the most common endocrine system disorders, chronic wasting disease, malnutrition and other diseases. These patients may induce the skin to brown or dark brown, distributed in the face, the back, joints and other parts exposed to friction or pressure on the site will be more obvious. Another example: chronic liver disease, may trigger facial chloasma or black around the eyes. In addition, melanosis melanoma patients were mostly accumulated at the face, especially the forehead, cheeks, ears and neck is very marked. There is also a type of skin diseases, especially some food allergy-induced skin diseases, such as: seafood, raw onions, raw garlic, hot pepper, pepper, leek, wine, fish, shrimp, seaweed, chicken, duck, pig hoof, and so on. as a result of individual differences, some individuals may also induce skin allergy, which block proliferation of measles, and finally left dark pigment of the skin.

Before the age of 25 because of adaptive pigmentation resulting black and spots, generally reversible, that is also able to come back slowly changing. Once the 25-year-old, skin situation began to decline, some lost their automatic spots reversible rotating, when the need for whitening products on the maintenance, to help restore the white skin.

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