Under normal circumstances, melanin cells continue to produce melanin, while melanin cells in the tyrosine under the tyrosinase is activated, generating dopa, and then dopa oxidation produce dopa quinone, then produce melanin. Melanin is the skin appear lustre of the pigment, some of the bud located in the basal layer.
Due to external factors and the internal factors that cause melanin cells metabolism disorder, and accumulation in the skin caused by uneven distribution of pigment and form melasma. There are two reasons cause melasma:
1. External factors: by stimulating the scarfskin(such as inappropriate whitening treatment, poor-quality cosmetics, etc.), ultraviolet radiation, massage, acne, acne scar, and so on.
2. Internal factors: hormonal imbalance, drug-taking (such as contraceptives, etc.), pregnancy, mental stress and so on.
Therefore, we should put forward more than two points, deal with skin problems in daily life should also pay attention to self-regulate, not take advantage of melanoma.
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