Melanin for skin on the role as a filter to protect the skin from ultraviolet radiation and physical damage.
Under normal circumstances, melanin cells continue to produce melanin, melanin cells in the tyrosine under the tyrosinase is activated, generating dopa, and dopa be oxidation produce dopa quinone, then produce melanin.
Due to external factors and Internal factors that cause melanin cells metabolism and accumulation in the skin caused by uneven distribution of pigment and form a stain. There are reasons form a stain of two categories:
1. External factors: by stimulating the skin (such as inappropriate whitening treatment, poor-quality cosmetics, etc.), ultraviolet radiation, massage, acne scar, and so on.
2. Internal factors: hormonal imbalance, drug-taking (such as contraceptives, etc.), pregnancy, mental stress and so on.
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